1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide

Base Information

Chemical Name:1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide
CAS No.:1762-50-1
Molecular Formula:C18H27 N3 O
Molecular Weight:301.432
Hs Code.:2933399090
European Community (EC) Number:217-173-5
UNII:ITI8Z5QC5C
DSSTox Substance ID:DTXSID20170097
Nikkaji Number:J23.953D
Wikidata:Q83039950
ChEMBL ID:CHEMBL1584435
Mol file:1762-50-1.mol

Synonyms:1762-50-1;1'-benzyl-1,4'-bipiperidine-4'-carboxamide;1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide;1-benzyl-4-piperidin-1-ylpiperidine-4-carboxamide;[1,4'-bipiperidine]-4'-carboxamide, 1'-(phenylmethyl)-;ITI8Z5QC5C;1'-Benzyl-[1,4'-bipiperidine]-4'-carboxamide;1'-(Phenylmethyl)-(1,4'-bipiperidine)-4'-carboxamide;1-Benzyl-4-carbamoyl-4-piperidinopiperidine;EINECS 217-173-5;(1,4'-Bipiperidine)-4'-carboxamide, 1'-(phenylmethyl)-;MLS000099942;1-Benzyl-4-piperidino-isonipecotamide;starbld0018863;UNII-ITI8Z5QC5C;SCHEMBL4630100;CHEMBL1584435;DTXSID20170097;HMS2491O04;STK741878;AKOS005526412;SMR000081117;WS-02980;FT-0662700;1-benzyl-4-carbamoyl-4-piperidino-piperidine;E71569;SR-01000293879;SR-01000293879-1;1-benzyl-4-(piperidin-1-yl)piperidine-4-carboxamide

Suppliers and Price of 1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1''-Benzyl-1,4''-bipiperidine-4''-carboxamide
250mg
$ 350.00

Biosynth Carbosynth
1'-Benzyl-1,4'-bipiperidine-4'-carboxamide
50 mg
$ 496.00

Biosynth Carbosynth
1'-Benzyl-1,4'-bipiperidine-4'-carboxamide
10 mg
$ 149.90

Biosynth Carbosynth
1'-Benzyl-1,4'-bipiperidine-4'-carboxamide
25 mg
$ 272.50

Biosynth Carbosynth
1'-Benzyl-1,4'-bipiperidine-4'-carboxamide
250 mg
$ 1640.00

Biosynth Carbosynth
1'-Benzyl-1,4'-bipiperidine-4'-carboxamide
100 mg
$ 901.00

American Custom Chemicals Corporation
1'-(PHENYLMETHYL)-[1,4'-BIPIPERIDINE]-4'-CARBOXAMIDE 95.00%
5MG
$ 499.46

AK Scientific
1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide
10mg
$ 252.00

Total 8 raw suppliers

Chemical Property of 1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide

Chemical Property:

Boiling Point:467.7°Cat760mmHg
Flash Point:236.6°C
PSA：49.57000
Density:1.142g/cm³
LogP:2.56850
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:301.215412493
Heavy Atom Count:22
Complexity:365

Purity/Quality:

99.9% ^*data from raw suppliers

1''-Benzyl-1,4''-bipiperidine-4''-carboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C2(CCN(CC2)CC3=CC=CC=C3)C(=O)N
Uses Piritramide intermediate.

Technology Process of 1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide

There total 4 articles about 1'-(Phenylmethyl)-[1,4'-bipiperidine]-4'-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 84254-97-7
1'-benzyl-octahydro-[1,4']bipyridinyl-4'-carbonitrile

: 1762-50-1
1'-benzyl-octahydro-[1,4']bipyridinyl-4'-carboxylic acid amide

Guidance literature:: 1'-benzyl-octahydro-[1,4']bipyridinyl-4'-carbonitrile; With sulfuric acid; In water; at 100 ℃; for 0.166667h; Heating / reflux;

With sodium hydroxide; In water; at 0 ℃; pH=9;

Reference yield: 92.0%

: 110-89-4
piperidine

: 3612-20-2
1-phenylmethyl-4-piperidone

: 75-86-5
2-hydroxy-2-methylpropanenitrile

: 1762-50-1
1'-benzyl-octahydro-[1,4']bipyridinyl-4'-carboxylic acid amide

Guidance literature:: piperidine; 1-phenylmethyl-4-piperidone; 2-hydroxy-2-methylpropanenitrile; With magnesium sulfate; In N,N-dimethyl acetamide; at 55 ℃; for 48h;

With sulfuric acid; water; at 100 ℃; for 0.166667h;

With sodium hydroxide; In water; at 0 ℃; pH=9;

Reference yield:

: 3612-20-2
1-phenylmethyl-4-piperidone

: 1762-50-1
1'-benzyl-octahydro-[1,4']bipyridinyl-4'-carboxylic acid amide

Guidance literature:: Multi-step reaction with 2 steps

1: methanol; water / 48 h / 20 °C

2: sulfuric acid / 0.17 h / 100 °C

With sulfuric acid; In methanol; water;