4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside

Base Information

• Chemical Name: 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside
• CAS No.: 865294-29-7
• Molecular Formula: C₆₃H₅₄O₁₉
• Molecular Weight: 1115.11
• Mol file: 865294-29-7.mol

Synonyms:4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside

Chemical Property of 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside

There total 3 articles about 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

4-methoxyphenyl 6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside (865294-28-6) + 2,3,4,6-tetra-O-benzoyl-1-O-trichloroacetimidoyl-α-D-galactopyranose (149707-75-5,149707-76-6,138479-78-4) → 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside (865294-29-7) + 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-α-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane;

DOI:10.1016/j.carres.2005.05.017

Reference yield:

C32H32O10 (865294-27-5) → 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside (865294-29-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / PdCl₂ / methanol / 5 h / 20 °C

2: 66 percent / TMSOTf / CH₂Cl₂

With trimethylsilyl trifluoromethanesulfonate; palladium dichloride; In methanol; dichloromethane;

DOI:10.1016/j.carres.2005.05.017

Reference yield:

4-methoxyphenyl 3-O-allyl-2,4-di-O-benzoyl-β-D-galactopyranoside (753500-16-2) → 4-methoxyphenyl 2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside (865294-29-7)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / pyridine / 6 h

2: 88 percent / PdCl₂ / methanol / 5 h / 20 °C

3: 66 percent / TMSOTf / CH₂Cl₂

With pyridine; trimethylsilyl trifluoromethanesulfonate; palladium dichloride; In methanol; dichloromethane;

DOI:10.1016/j.carres.2005.05.017

upstream raw materials:

4-methoxyphenyl 6-O-acetyl-2,4-di-O-benzoyl-β-D-galactopyranoside

2,3,4,6-tetra-O-benzoyl-1-O-trichloroacetimidoyl-α-D-galactopyranose

C₃₂H₃₂O₁₀

4-methoxyphenyl 3-O-allyl-2,4-di-O-benzoyl-β-D-galactopyranoside

Downstream raw materials:

2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl-(1->3)-6-O-acetyl-2,4-di-O-benzoyl-α-D-galactopyranosyl trichloroacetimidate