(5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Base Information

Chemical Name:(5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid
CAS No.:108908-49-2
Molecular Formula:C₁₃H₁₁ClN₂O₈
Molecular Weight:358.692
Hs Code.:

Synonyms:(5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Suppliers and Price of (5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

There total 3 articles about (5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.2%

: 108908-48-1
(Z)-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

: 108908-54-9
(5E)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

: 108908-49-2
(5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Guidance literature:: With sulfuryl dichloride; In acetic acid; at 50 - 55 ℃; for 5h;
DOI:10.1248/cpb.34.3458

Reference yield:

: 108908-46-9
p-nitrobenzyl chloroacetate

: 108908-49-2
(5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Guidance literature:: Multi-step reaction with 3 steps

1: 54.5 percent / K₂CO₃ / ethyl acetate; dimethylformamide / 5 h / 50 °C

2: 92.7 percent / TFA / various solvent(s) / 2 h / Ambient temperature

3: 28.2 percent / sulfuryl chloride / acetic acid / 5 h / 50 - 55 °C

With sulfuryl dichloride; potassium carbonate; trifluoroacetic acid; In acetic acid; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.34.3458

Reference yield:

: 108908-47-0
tert-butyl (Z)-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyrate

: 108908-49-2
(5Z)-4-chloro-2-p-nitrobenzyloxycarbonylmethoxyimino-3-oxobutyric acid

Guidance literature:: Multi-step reaction with 2 steps

1: 92.7 percent / TFA / various solvent(s) / 2 h / Ambient temperature

2: 28.2 percent / sulfuryl chloride / acetic acid / 5 h / 50 - 55 °C

With sulfuryl dichloride; trifluoroacetic acid; In acetic acid;
DOI:10.1248/cpb.34.3458