imidazole-1-carboxylic acid methylphenylamide

Base Information

• Chemical Name: imidazole-1-carboxylic acid methylphenylamide
• CAS No.: 92289-43-5
• Molecular Formula: C₁₁H₁₁N₃O
• Molecular Weight: 201.228
• Mol file: 92289-43-5.mol

Synonyms:imidazole-1-carboxylic acid methylphenylamide

Chemical Property of imidazole-1-carboxylic acid methylphenylamide

Chemical Property:

• Melting Point: 72.5-73.5 °C
• Boiling Point: 344.7±25.0 °C(Predicted)
• Density: 1.14±0.1 g/cm3(Predicted)

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of imidazole-1-carboxylic acid methylphenylamide

There total 3 articles about imidazole-1-carboxylic acid methylphenylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,1'-carbonyldiimidazole (530-62-1) + N-methylaniline (100-61-8) → imidazole-1-carboxylic acid methylphenylamide (92289-43-5)

Guidance literature:

In tetrahydrofuran; for 20h; Reflux;

DOI:10.1039/c0cc04912c

Reference yield: 44.0%

1H-imidazole (288-32-4) + N-phenyl-N-methylcarbamoyl chloride (4285-42-1) → imidazole-1-carboxylic acid methylphenylamide (92289-43-5)

Guidance literature:

In tetrahydrofuran; toluene; at 0 - 20 ℃; for 2h;

DOI:10.1002/cmdc.201800393

Reference yield:

→ imidazole-1-carboxylic acid methylphenylamide (92289-43-5)

Guidance literature:

upstream raw materials:

1,1'-carbonyldiimidazole

N-methylaniline

1H-imidazole

N-phenyl-N-methylcarbamoyl chloride

Downstream raw materials:

N-methyl-N-phenyl-carbamoyl cyanide

1,1-diisopropyl-3-methyl-3-phenylurea

N'-cyclohexyl-N-methyl-N-phenylurea

N-methyl-N-phenyl-1H-indole-3-carboxamide