Technology Process of uridine 5'-diphospho-2-acetamido-6-phenylacetamido-2,6-dideoxy-α-D-glucopyranoside
There total 4 articles about uridine 5'-diphospho-2-acetamido-6-phenylacetamido-2,6-dideoxy-α-D-glucopyranoside which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydrogencarbonate;
In
water; acetonitrile;
at 0 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium on activated charcoal; hydrogen / methanol; water / 1 h / 3000.3 Torr
2: sodium hydrogencarbonate / water; acetonitrile / 4 h / 0 °C
With
palladium on activated charcoal; hydrogen; sodium hydrogencarbonate;
In
methanol; water; acetonitrile;
DOI:10.1039/c1cc14034e
- Guidance literature:
-
Multi-step reaction with 3 steps
1: inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; ATP; magnesium chloride / water / 37 °C / pH 8 / aq. buffer; Enzymatic reaction
2: palladium on activated charcoal; hydrogen / methanol; water / 1 h / 3000.3 Torr
3: sodium hydrogencarbonate / water; acetonitrile / 4 h / 0 °C
With
palladium on activated charcoal; inorganic pyrophosphatase cloned from Pasteurella multocida strain P-1059; N-acetylglucosamine-1-phosphate uridylyltransferase cloned from Pasteurella multocida strain P-1059 (ATCC15742); N-acetylhexosamine 1-kinase cloned from Bifidobacterium longum ATCC55813; hydrogen; sodium hydrogencarbonate; ATP; magnesium chloride;
In
methanol; water; acetonitrile;
DOI:10.1039/c1cc14034e