2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole

Base Information

Chemical Name:2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole
CAS No.:35463-75-3
Molecular Formula:C₁₈H₁₉N₃S
Molecular Weight:309.435
Hs Code.:
UNII:Z85HX53QTH
DSSTox Substance ID:DTXSID001244344
Nikkaji Number:J590.121I
ChEMBL ID:CHEMBL282234

Synonyms:2-(4-benzylpiperazin-1-yl)-1,3-benzothiazole;35463-75-3;Z85HX53QTH;CHEMBL282234;2-(4-Benzyl-piperazin-1-yl)-benzothiazole;2-[4-(Phenylmethyl)-1-piperazinyl]benzothiazole;2-(4-(Phenylmethyl)piperazin-1-yl)-1,3-benzothiazole;2-(4-(Phenylmethyl)-1-piperazinyl)benzothiazole;Benzothiazole, 2-(4-(phenylmethyl)-1-piperazinyl)-;Benzothiazole, 2-[4-(phenylmethyl)-1-piperazinyl]-;2-(4-benzylpiperazino)-1,3-benzothiazole;D0L1NS;UNII-Z85HX53QTH;Oprea1_030694;MLS001166194;SCHEMBL7760900;DTXSID001244344;HMS2852D05;BDBM50041381;AKOS005101332;7P-339S;1-(2-Benzothiazolyl)-4-benzylpiperazine;SMR000550026;2-(4-benzylpiperazin-1-yl)benzo[d]thiazole;EN300-12592527;Z86230191;F5773-3520

Suppliers and Price of 2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole

Chemical Property:

XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:309.12996879
Heavy Atom Count:22
Complexity:350

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)C3=NC4=CC=CC=C4S3

Technology Process of 2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole

There total 5 articles about 2-(4-Benzylpiperazin-1-yl)-1,3-benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 615-20-3
2-chlorobenzo[d][1,3]thiazole

: 2759-28-6
1-phenylmethylpiperazine

: 35463-75-3
2-(4-benzyl-piperazin-1-yl)-benzothiazole

Guidance literature:: With sodium hydrogencarbonate; In water; isopropyl alcohol; Heating;
DOI:10.1021/jm00035a012

Reference yield: 90.0%

: 2759-28-6
1-phenylmethylpiperazine

: 7144-49-2
2-methanesulfonylbenzothiazole

: 35463-75-3
2-(4-benzyl-piperazin-1-yl)-benzothiazole

Guidance literature:: With sodium hydrogencarbonate; at 60 - 80 ℃; for 0.5h;
DOI:10.1021/jm00035a012

Reference yield:

: 117883-09-7
2-methylthiobenzothiazole hydroiodide

: 35463-75-3
2-(4-benzyl-piperazin-1-yl)-benzothiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 72.4 percent / 3-chloroperbenzoic acid / CH₂Cl₂ / 17 h / Ambient temperature

2: 90 percent / sodium bicarbonate / 0.5 h / 60 - 80 °C

With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane;
DOI:10.1021/jm00035a012