Technology Process of 1-bromomethyl-4-dodeca-1,3-diynyl-benzene
There total 5 articles about 1-bromomethyl-4-dodeca-1,3-diynyl-benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine; bromotriphenylphosphonium bromide;
In
acetonitrile;
at 0 ℃;
for 1h;
DOI:10.1071/CH09639
- Guidance literature:
-
Multi-step reaction with 2 steps
1: piperidine / copper(l) chloride / 1 h / 0 - 20 °C
2: pyridine; triphenylphosphine dibromide 1:1 addition complex / acetonitrile / 1 h / 20 °C
With
piperidine; pyridine; triphenylphosphine dibromide 1:1 addition complex;
copper(l) chloride;
In
acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: triethylamine; triphenylphosphine / palladium diacetate / 2 h / Heating / reflux
2: sodium tetrahydroborate / ethanol / 20 °C
3: potassium carbonate / methanol / 2 h / 20 °C
4: piperidine / copper(l) chloride / 1 h / 0 - 20 °C
5: pyridine; triphenylphosphine dibromide 1:1 addition complex / acetonitrile / 1 h / 20 °C
With
piperidine; pyridine; sodium tetrahydroborate; potassium carbonate; triphenylphosphine dibromide 1:1 addition complex; triethylamine; triphenylphosphine;
palladium diacetate; copper(l) chloride;
In
methanol; ethanol; acetonitrile;
