1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate

Base Information

• Chemical Name: 1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate
• CAS No.: 1608483-47-1
• Molecular Formula: C₃₉H₄₉N₃O₁₀
• Molecular Weight: 719.832

Synonyms:1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate

Chemical Property of 1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate

There total 4 articles about 1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

N1-[3,4-bis(benzyloxy)benzoyl]-N4-acetyl spermidine TFA salt (1608483-45-9) + C9H12O6 (1608483-46-0) → 1-{N1'-[3'',4''-bis(benzyloxy)benzoyl]-N4'-acetylspermidinyl}-2-isopropyl citrate (1608483-47-1)

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 36h; Molecular sieve; Inert atmosphere;

DOI:10.1002/ejoc.201301340 DOI:10.1002/ejoc.201301340

Reference yield:

2-Hydroxy-1,2,3-propanetricarboxylic Acid 2-Isopropyl Ester (83966-24-9) → 1-{N1'-[3'',4''-bis(benzyloxy)benzoyl]-N4'-acetylspermidinyl}-2-isopropyl citrate (1608483-47-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / tetrahydrofuran / 1 h / 20 °C / Molecular sieve; Inert atmosphere

2: triethylamine / N,N-dimethyl-formamide / 36 h / 20 °C / Molecular sieve; Inert atmosphere

With triethylamine; dicyclohexyl-carbodiimide; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201301340

Reference yield:

N1-[3,4-bis(benzyloxy)-benzoyl]-N8-tert-butyloxycarbonyl-spermidine (1264499-14-0) → 1-{N1'-[3'',4''-bis(benzyloxy)benzoyl]-N4'-acetylspermidinyl}-2-isopropyl citrate (1608483-47-1)

Guidance literature:

Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 18 h / 20 °C / Inert atmosphere

2: dichloromethane / 5.5 h / 0 - 20 °C / Inert atmosphere

3: triethylamine / N,N-dimethyl-formamide / 36 h / 20 °C / Molecular sieve; Inert atmosphere

With triethylamine; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/ejoc.201301340

upstream raw materials:

C₃₅H₄₅N₃O₆

N₁-[3,4-bis(benzyloxy)benzoyl]-N₄-acetyl spermidine TFA salt

C₉H₁₂O₆

2-Hydroxy-1,2,3-propanetricarboxylic Acid 2-Isopropyl Ester

Downstream raw materials:

C₄₃H₅₂N₄O₁₂

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1608483-47-1 1-{N^1'-[3'',4''-bis(benzyloxy)benzoyl]-N^4'-acetylspermidinyl}-2-isopropyl citrate

Send

Send

Metric Ton KG G Pound L ML

Send

Send