C₃₀H₄₈N₂O₄

Base Information

• Chemical Name: C₃₀H₄₈N₂O₄
• CAS No.: 848731-55-5
• Molecular Formula: C₃₀H₄₈N₂O₄
• Molecular Weight: 500.722
• Mol file: 848731-55-5.mol

Synonyms:C₃₀H₄₈N₂O₄

Chemical Property of C₃₀H₄₈N₂O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₄₈N₂O₄

There total 17 articles about C₃₀H₄₈N₂O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

C31H46N2O5 (848731-62-4) → C30H48N2O4 (848731-55-5)

Guidance literature:

With potassium hydroxide; In ethanol; at 90 ℃;

DOI:10.1021/ol050038m

Reference yield:

C19H22N2O6S → C30H48N2O4 (848731-55-5)

Guidance literature:

Multi-step reaction with 16 steps

1.1: tetrahydrofuran; diethyl ether / -78 - -10 °C

2.1: 98 percent / KHMDS / tetrahydrofuran / -78 - 0 °C

3.1: aq. HF / acetonitrile / 20 °C

3.2: 87 percent / Et₃N / CH₂Cl₂ / -78 - 20 °C

4.1: 92 percent / 2,6-di-tert-butyl-4-methylpyridine; BCl₃ / CH₂Cl₂; heptane / 15 h / 20 °C

5.1: imidazole / acetonitrile

6.1: NaBH₄ / methanol

7.1: Et₃N / CH₂Cl₂

8.1: Na; naphthalene / 1,2-dimethoxy-ethane; tetrahydrofuran / -78 °C

9.1: NaBH₃CN; AcOH / acetonitrile / 20 °C

10.1: 75 percent / (PCy₃)2Cl₂Ru=CHPh / CH₂Cl₂ / 7 h / Heating

11.1: 93 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

12.1: 83 percent / HCl / tetrahydrofuran; H₂O / 20 °C

13.1: 89 percent / NaHMDS / dimethylformamide / 20 °C

14.1: 85 percent / tris(dimethylamino)sulfur (trimethylsilyl)difluoride / N,N-dimethyl-acetamide / 100 °C

15.1: 90 percent / KOH / ethanol / 90 °C

With 1H-imidazole; hydrogenchloride; potassium hydroxide; sodium tetrahydroborate; 2,6-di-tert-butyl-4-methylpyridine; naphthalene; hydrogen fluoride; tris(dimethylamino)sulfonium trimethylsilyldifluoride; hydrogen; sodium hexamethyldisilazane; sodium; boron trichloride; potassium hexamethylsilazane; sodium cyanoborohydride; acetic acid; triethylamine; palladium on activated charcoal; Grubbs catalyst first generation; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; ethanol; n-heptane; dichloromethane; N,N-dimethyl acetamide; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; 1.1: Grignarg reaction / 2.1: Swern oxidation / 3.1: Wittig reaction;

DOI:10.1021/ol050038m

Reference yield:

C20H24N2O5S → C30H48N2O4 (848731-55-5)

Guidance literature:

Multi-step reaction with 17 steps

1.1: O₃; NaHCO₃ / CH₂Cl₂; methanol / -78 °C

1.2: 90 percent / Me₂S / -78 - 20 °C

2.1: tetrahydrofuran; diethyl ether / -78 - -10 °C

3.1: 98 percent / KHMDS / tetrahydrofuran / -78 - 0 °C

4.1: aq. HF / acetonitrile / 20 °C

4.2: 87 percent / Et₃N / CH₂Cl₂ / -78 - 20 °C

5.1: 92 percent / 2,6-di-tert-butyl-4-methylpyridine; BCl₃ / CH₂Cl₂; heptane / 15 h / 20 °C

6.1: imidazole / acetonitrile

7.1: NaBH₄ / methanol

8.1: Et₃N / CH₂Cl₂

9.1: Na; naphthalene / 1,2-dimethoxy-ethane; tetrahydrofuran / -78 °C

10.1: NaBH₃CN; AcOH / acetonitrile / 20 °C

11.1: 75 percent / (PCy₃)2Cl₂Ru=CHPh / CH₂Cl₂ / 7 h / Heating

12.1: 93 percent / H₂ / Pd/C / ethyl acetate / 6 h / 20 °C

13.1: 83 percent / HCl / tetrahydrofuran; H₂O / 20 °C

14.1: 89 percent / NaHMDS / dimethylformamide / 20 °C

15.1: 85 percent / tris(dimethylamino)sulfur (trimethylsilyl)difluoride / N,N-dimethyl-acetamide / 100 °C

16.1: 90 percent / KOH / ethanol / 90 °C

With 1H-imidazole; hydrogenchloride; potassium hydroxide; sodium tetrahydroborate; 2,6-di-tert-butyl-4-methylpyridine; naphthalene; hydrogen fluoride; tris(dimethylamino)sulfonium trimethylsilyldifluoride; hydrogen; sodium hexamethyldisilazane; sodium; boron trichloride; potassium hexamethylsilazane; sodium cyanoborohydride; sodium hydrogencarbonate; ozone; acetic acid; triethylamine; palladium on activated charcoal; Grubbs catalyst first generation; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; diethyl ether; ethanol; n-heptane; dichloromethane; N,N-dimethyl acetamide; water; ethyl acetate; N,N-dimethyl-formamide; acetonitrile; 2.1: Grignarg reaction / 3.1: Swern oxidation / 4.1: Wittig reaction;

DOI:10.1021/ol050038m

upstream raw materials:

C₃₁H₄₆N₂O₅

C₂₅H₃₂N₂O₆S

C₃₁H₄₆N₂O₆SSi

C₃₃H₆₂N₂O₄Si₂

Downstream raw materials:

C₄₀H₆₈N₂O₅Si

C₃₈H₅₇IN₂O₄

(CH₂)10CCH₂OCH(CH₂)3O((C(CH₃)3)(CH₃)2Si)(CH₂CHCH₂NCCHCH)CH₂CH₂NCH(OCH₂C₆H₄OCH₃)CHO

C₃₈H₅₉IN₂O₄