N-Isopropyl-17-hydroxycamptothecin Lactam

Base Information

• Chemical Name: N-Isopropyl-17-hydroxycamptothecin Lactam
• CAS No.: 118514-62-8
• Molecular Formula: C₂₃H₂₃N₃O₄
• Molecular Weight: 405.453

Synonyms:N-Isopropyl-17-hydroxycamptothecin Lactam

Chemical Property of N-Isopropyl-17-hydroxycamptothecin Lactam

Chemical Property:

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Technology Process of N-Isopropyl-17-hydroxycamptothecin Lactam

There total 1 articles about N-Isopropyl-17-hydroxycamptothecin Lactam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 12.0%

camptothecin-21-isopropylamide (69203-72-1) → camptothecin (7689-03-4,91926-09-9) + N-Isopropyl-17-hydroxycamptothecin Lactam (118514-62-8) + N-Isopropyl-17-oxocamptothecin Lactam (118514-63-9)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 72h; Ambient temperature;

DOI:10.1021/jm00123a038

upstream raw materials:

camptothecin-21-isopropylamide

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