(-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide

Base Information

Chemical Name:(-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide
CAS No.:1214281-89-6
Molecular Formula:C₂₁H₂₈F₃NO₄
Molecular Weight:415.453
Hs Code.:

Synonyms:(-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide

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Chemical Property of (-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide

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Technology Process of (-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide

There total 1 articles about (-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1214281-84-1
(-)-(4R,5R)-5-[(S)-1-hydroxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide

: 106-95-6
allyl bromide

: 1214281-89-6
(-)-(4R,5R)-5-[(S)-1-allyloxy-3-phenyl-1-(trifluoromethyl)propyl]-2,2-dimethyl-[1,3]-dioxolane-4-(dimethyl)carboxylamide

Guidance literature:: With potassium tert-butylate; tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 20 ℃; for 4h; Inert atmosphere;
DOI:10.1002/ejoc.200901153