Methyl 2-[(3-acetyloxy-4,5-dimethoxyoxan-2-yl)methoxy]acetate

Base Information

Chemical Name:Methyl 2-[(3-acetyloxy-4,5-dimethoxyoxan-2-yl)methoxy]acetate
CAS No.:134121-14-5
Molecular Formula:C₁₃H₂₂O₈
Molecular Weight:306.313
Hs Code.:
DSSTox Substance ID:DTXSID20928459
Mol file:134121-14-5.mol

Synonyms:4-AMMMG;4-O-acetyl-1,5-anhydro-O-(methoxycarbonylmethyl)di-O-methylglucitol;4-O-acetyl-1,5-anhydro-O-(methoxycarbonylmethyl)di-O-methylglucitol, 2-O-(methoxycarbonylmethyl)-3,6-di-O-methyl isomer;4-O-acetyl-1,5-anhydro-O-(methoxycarbonylmethyl)di-O-methylglucitol, 3-O-(methoxycarbonylmethyl)-2,6-di-O-methyl isomer

Suppliers and Price of Methyl 2-[(3-acetyloxy-4,5-dimethoxyoxan-2-yl)methoxy]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 2-[(3-acetyloxy-4,5-dimethoxyoxan-2-yl)methoxy]acetate

Chemical Property:

Vapor Pressure:2.86E-06mmHg at 25°C
Boiling Point:389.4°Cat760mmHg
Flash Point:170.1°C
PSA：89.52000
Density:1.18g/cm³
LogP:-0.46350
XLogP3:-0.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:306.13146766
Heavy Atom Count:21
Complexity:345

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1C(OCC(C1OC)OC)COCC(=O)OC

Technology Process of Methyl 2-[(3-acetyloxy-4,5-dimethoxyoxan-2-yl)methoxy]acetate

There total 3 articles about Methyl 2-[(3-acetyloxy-4,5-dimethoxyoxan-2-yl)methoxy]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 134407-58-2
((2R,3R,4R,5S)-3-Benzyloxy-4,5-dimethoxy-tetrahydro-pyran-2-ylmethoxy)-acetic acid methyl ester

: 134121-14-5
4-O-acetyl-1,5-anhydro-6-O-(methoxycarbonylmethyl)-2,3-di-O-methyl-D-glucitol

Guidance literature:: With hydrogen; palladium; Yield given. Multistep reaction; 1.) EtOH, 101 kPa, 18 h, 2.) acetylation;
DOI:10.1016/0008-6215(91)84145-5

Reference yield:

: 83075-53-0,89177-22-0,129454-52-0,51433-19-3
methyl 4-O-benzyl-2,3-di-O-methyl-α-D-glucopyranoside

: 134121-14-5
4-O-acetyl-1,5-anhydro-6-O-(methoxycarbonylmethyl)-2,3-di-O-methyl-D-glucitol

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH / 1.) THF, reflux, 4 h, 2.) 0 deg C, 15 min

2: 73 percent / triethylsilane, trimethylsilyl methanesulfonate, BF₃*Et₂O

3: 1.) H₂ / 1.) Pd / 1.) EtOH, 101 kPa, 18 h, 2.) acetylation

With triethylsilane; trimethylsilyl methanesulfonate; boron trifluoride diethyl etherate; hydrogen; sodium hydride; palladium;
DOI:10.1016/0008-6215(91)84145-5

Reference yield:

: 134407-57-1
((2R,3R,4S,5R,6S)-3-Benzyloxy-4,5,6-trimethoxy-tetrahydro-pyran-2-ylmethoxy)-acetic acid methyl ester

: 134121-14-5
4-O-acetyl-1,5-anhydro-6-O-(methoxycarbonylmethyl)-2,3-di-O-methyl-D-glucitol

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / triethylsilane, trimethylsilyl methanesulfonate, BF₃*Et₂O

2: 1.) H₂ / 1.) Pd / 1.) EtOH, 101 kPa, 18 h, 2.) acetylation

With triethylsilane; trimethylsilyl methanesulfonate; boron trifluoride diethyl etherate; hydrogen; palladium;
DOI:10.1016/0008-6215(91)84145-5