N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine

Base Information

• Chemical Name: N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine
• CAS No.: 240403-67-2
• Molecular Formula: C₂₁H₂₄N₂O₃S
• Molecular Weight: 384.499

Synonyms:N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine

Chemical Property of N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine

There total 4 articles about N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-(2-Methoxyphenyl)piperazine (35386-24-4) + 4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-ylacetic acid (107866-80-8) → N1-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N4-(o-methoxyphenyl)piperazine (240403-67-2)

Guidance literature:

With benzotriazol-1-ol; dicyclohexyl-carbodiimide; In dichloromethane; Ambient temperature;

DOI:10.1021/jm981094e

Reference yield: 65.0%

1-(2-Methoxyphenyl)piperazine (35386-24-4) + 5-Carbethoxyethyl-4-oxo-4,5,6,7-tetrahydrobenzo(b)thiophene (107866-86-4) → N1-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N4-(o-methoxyphenyl)piperazine (240403-67-2)

Guidance literature:

With trimethylaluminum; In hexane; dichloromethane; for 48h; Heating;

DOI:10.1021/jm981094e

Reference yield:

4-keto-4,5,6,7-tetrahydrothianaphthene (13414-95-4) → N1-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N4-(o-methoxyphenyl)piperazine (240403-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LDA / 1.) -70 deg C

2: 65 percent / Me₃Al / hexane; CH₂Cl₂ / 48 h / Heating

With trimethylaluminum; lithium diisopropyl amide; In hexane; dichloromethane;

DOI:10.1021/jm981094e

upstream raw materials:

1-(2-Methoxyphenyl)piperazine

5-Carbethoxyethyl-4-oxo-4,5,6,7-tetrahydrobenzo(b)thiophene

4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-ylacetic acid

4-keto-4,5,6,7-tetrahydrothianaphthene

Downstream raw materials:

C₂₃H₂₈N₂O₄S

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 240403-67-2 N¹-<(4-oxo-4,5,6,7-tetrahydrobenzothiophene-5-yl)acetyl>-N⁴-(o-methoxyphenyl)piperazine

Send

Send

Metric Ton KG G Pound L ML

Send

Send