4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Base Information

Chemical Name:4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride
CAS No.:250292-72-9
Molecular Formula:C₁₉H₂₂FNO₅
Molecular Weight:363.386
Hs Code.:

Synonyms:4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Suppliers and Price of 4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

There total 6 articles about 4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 250292-66-1
4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl alcohol

: 250292-72-9
4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Guidance literature:: With diethylamino-sulfur trifluoride; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/jo991085t

Reference yield:

: 4101-32-0
4',5'-dimethoxy-2'-nitroacetophenone

: 250292-72-9
4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Guidance literature:: Multi-step reaction with 5 steps

1: 77 percent / sodium borohydride / ethanol / 19 h

2: 85 percent / phosphorus tribromide / CH₂Cl₂ / 2.5 h

3: 91 percent / potassium carbonate / dimethylformamide / 4.5 h / 20 °C

4: 100 percent / sodium borohydride / ethanol / 3 h / 20 °C

5: 59 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 1 h / 20 °C

With sodium tetrahydroborate; diethylamino-sulfur trifluoride; phosphorus tribromide; potassium carbonate; In ethanol; dichloromethane; N,N-dimethyl-formamide; 1: Reduction / 2: Bromination / 3: Etherification / 4: Reduction / 5: Fluorination;
DOI:10.1021/jo991085t

Reference yield:

: 37942-55-5
1-(4,5-Dimethoxy-2-nitrophenyl)-ethanol

: 250292-72-9
4-(4',5'-dimethoxy-α'-methyl-2'-nitrobenzyloxy)-3,5-dimethylbenzyl fluoride

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / phosphorus tribromide / CH₂Cl₂ / 2.5 h

2: 91 percent / potassium carbonate / dimethylformamide / 4.5 h / 20 °C

3: 100 percent / sodium borohydride / ethanol / 3 h / 20 °C

4: 59 percent / diethylaminosulfur trifluoride / CH₂Cl₂ / 1 h / 20 °C

With sodium tetrahydroborate; diethylamino-sulfur trifluoride; phosphorus tribromide; potassium carbonate; In ethanol; dichloromethane; N,N-dimethyl-formamide; 1: Bromination / 2: Etherification / 3: Reduction / 4: Fluorination;
DOI:10.1021/jo991085t