4-hydroxy-2-methylbenzofuran

Base Information

• Chemical Name: 4-hydroxy-2-methylbenzofuran
• CAS No.: 3610-14-8
• Molecular Formula: C₉H₈O₂
• Molecular Weight: 148.161
• Mol file: 3610-14-8.mol

Synonyms:4-hydroxy-2-methylbenzofuran

Chemical Property of 4-hydroxy-2-methylbenzofuran

Chemical Property:

Purity/Quality:

2-methyl-4-Benzofuranol 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-hydroxy-2-methylbenzofuran

There total 1 articles about 4-hydroxy-2-methylbenzofuran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-allyloxyphenol (1616-51-9) → 4-hydroxy-2-methylbenzofuran (3610-14-8) + 6-hydroxy-2-methylbenzofuran (54584-24-6)

Guidance literature:

With sodium carbonate; p-benzoquinone; dichloro bis(acetonitrile) palladium(II); In 1,4-dioxane; at 65 ℃; for 5h; Title compound not separated from byproducts;

DOI:10.1021/ol051264z

Reference yield: 74.0%

4-hydroxy-2-methylbenzofuran (3610-14-8) → 2-methylbenzofuran-4,7-dione (138518-17-9)

Guidance literature:

With potassium dihydrogenphosphate; potassiuim nitrosodisulfonate; In ethanol; water; at 0 ℃; for 1h;

DOI:10.1016/0040-4020(96)00484-X

Reference yield:

4-hydroxy-2-methylbenzofuran (3610-14-8) + Ethyl 4-(bromomethyl)benzoate (26496-94-6) → ethyl 4-(2-methyl-4-benzofuranyloxymethyl)benzoate

Guidance literature:

With sodium iodide; potassium carbonate; In ethanol;

upstream raw materials:

3-allyloxyphenol

Downstream raw materials:

2-methylbenzofuran-4,7-dione