(1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine

Base Information

Chemical Name:(1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine
CAS No.:639072-83-6
Molecular Formula:C₂HF₃O₂*C₂₁H₂₂F₂N₂O
Molecular Weight:470.439
Hs Code.:

Synonyms:(1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine

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Chemical Property of (1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine

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Technology Process of (1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine

There total 1 articles about (1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 635724-44-6
4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrole trifluoroacetic acid salt

: 13734-41-3
t-Boc-L-valine

: 76-05-1
trifluoroacetic acid

: 639072-83-6
(1S)-1-{[4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro1H-pyrrol-1-yl]carbonyl}-2-methylpropylamine

Guidance literature:: 4-(2,5-difluorophenyl)-2-phenyl-2,5-dihydro-1H-pyrrole trifluoroacetic acid salt; t-Boc-L-valine; With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In DMF (N,N-dimethyl-formamide); at 23 ℃; for 20h;

With trifluoroacetic acid; In dichloromethane; for 0.75h;

trifluoroacetic acid;