4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Base Information

• Chemical Name: 4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester
• CAS No.: 1033880-16-8
• Molecular Formula: C₁₂H₂₂N₂O₄
• Molecular Weight: 258.318

Synonyms:4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Chemical Property of 4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

1-(tert-Butyl) 3-ethyl 4-amino-1,3-pyrrolidinedicarboxylate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
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Technology Process of 4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

There total 1 articles about 4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(1-phenyl-ethylamino)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester (1033880-14-6) → 4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester (1033880-16-8)

Guidance literature:

With hydrogen; Pearlman's catalist; In ethanol; at 20 ℃; under 3102.97 Torr;

Reference yield:

4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester (1033880-16-8) + (S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoic acid (402958-96-7) → 4-(2-{2-cyclohexyl-2-[(pyrazine-2-carbonyl)-amino]-acetylamino}-3,3-dimethyl-butyrylamino)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

Guidance literature:

(S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 25 ℃; for 0.333333h;

4-amino-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester; With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 18h;

upstream raw materials:

4-(1-phenyl-ethylamino)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-ethyl ester

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