(2-Aminophenyl)phosphonic acid

Base Information

Chemical Name:(2-Aminophenyl)phosphonic acid
CAS No.:7472-16-4
Molecular Formula:C6H8NO3P
Molecular Weight:173.108
Hs Code.:2931900090
European Community (EC) Number:831-049-3
NSC Number:402274
UNII:MVH27H43YT
DSSTox Substance ID:DTXSID10225702
Nikkaji Number:J135.897I
Wikidata:Q83104799
Mol file:7472-16-4.mol

Synonyms:(2-Aminophenyl)phosphonic acid;7472-16-4;2-Aminophenylphosphonic acid;Phosphonic acid, (o-aminophenyl)-;2-Aminobenzenephosphonic acid;(o-Aminophenyl)phosphonic acid;Phosphonic acid, (2-aminophenyl)-;NSC 402274;BRN 2937141;MVH27H43YT;NSC-402274;4-16-00-01127 (Beilstein Handbook Reference);(2-Amino-phenyl)-phosphonic acid;aminophenyl phosphonic acid;EC-000.1683;UNII-MVH27H43YT;2-AMINOPHENYLPHOSPHONIC ACID;ON REQUEST;SCHEMBL232481;DTXSID10225702;NSC402274;AKOS006278200;P-(2-AMINOPHENYL)PHOSPHONIC ACID;LS-106437;CS-0245006;PHOSPHONIC ACID, P-(2-AMINOPHENYL)-;EN300-2980526;Z1198157927

Suppliers and Price of (2-Aminophenyl)phosphonic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-AMINOPHENYLPHOSPHONIC ACID 95.00%
5MG
$ 497.09

A2B
2-Aminophenylphosphonicacid 95.0%
1g
$ 1030.00

A2B
2-Aminophenylphosphonicacid 95.0%
500mg
$ 813.00

A2B
2-Aminophenylphosphonicacid 95.0%
250mg
$ 532.00

Total 8 raw suppliers

Chemical Property of (2-Aminophenyl)phosphonic acid

Chemical Property:

Vapor Pressure:2.88E-08mmHg at 25°C
Melting Point:294-296 °C (decomp)
Boiling Point:433°C at 760 mmHg
PKA:pK2: 4.10;pK3: 7.29 (25°C)
Flash Point:215.7°C
PSA：93.36000
Density:1.51g/cm³
LogP:0.65300
XLogP3:-0.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:173.02418011
Heavy Atom Count:11
Complexity:179

Purity/Quality:

98% ^*data from raw suppliers

2-AMINOPHENYLPHOSPHONIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N)P(=O)(O)O

Technology Process of (2-Aminophenyl)phosphonic acid

There total 6 articles about (2-Aminophenyl)phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: diisopropyl 2-(t-butoxycarbonylamino)phenylphosphonate

: 7472-16-4
2-aminophenylphosphonic acid

Guidance literature:: With trimethylsilyl bromide; allyl-trimethyl-silane; In dichloromethane; Reagent/catalyst; Reflux; Inert atmosphere;
DOI:10.1007/s00706-017-2058-x

Reference yield:

: 7506-82-3
2-bromophenylphosphonic acid

: 7472-16-4
2-aminophenylphosphonic acid

Guidance literature:: With ammonia; water;
DOI:10.1021/ja01123a049

Reference yield:

: 615-43-0
2-iodophenylamine

: 7472-16-4
2-aminophenylphosphonic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 90 percent / aq. NaOH / 5 h / 20 °C

2: 20 percent / Et₃N; tetrakis(triphenylphosphine)palladium / toluene / 8 h / Heating

3: aq. NaOH / methanol / 2 h / Heating

With sodium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In methanol; toluene;
DOI:10.1016/j.ejmech.2006.03.023