6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Base Information

Chemical Name:6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde
CAS No.:872710-11-7
Molecular Formula:C₂₄H₂₈O₃
Molecular Weight:364.485
Hs Code.:

Synonyms:6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Suppliers and Price of 6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

There total 5 articles about 6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 847585-92-6
6-hydroxy-1-methyl-3,4-dihydro-naphthalene-2-carbaldehyde

: 872710-10-6
(4-isobutyl-2-methoxyphenyl)methanol

: 872710-11-7
6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Guidance literature:: (4-isobutyl-2-methoxyphenyl)methanol; With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 1h;

6-hydroxy-1-methyl-3,4-dihydro-naphthalene-2-carbaldehyde; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;
DOI:10.1021/acs.jmedchem.7b00785

Reference yield:

: 57568-45-3
1-methoxy-3-(2-methylpropyl)benzene

: 872710-11-7
6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1.1: tert.-butyl lithium; N,N,N,N,-tetramethylethylenediamine / tetrahydrofuran; pentane; hexane / 4 h / -78 - 0 °C

1.2: 4 h / 0 °C

2.1: sodium tetrahydroborate / methanol / 1.5 h / 0 °C

3.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C

3.2: 4 h / 20 °C

With sodium tetrahydroborate; carbon tetrabromide; N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; triphenylphosphine; In tetrahydrofuran; methanol; hexane; dichloromethane; pentane;
DOI:10.1021/acs.jmedchem.7b00785

Reference yield:

: 872710-09-3
4-isobutyl-2-methoxybenzaldehyde

: 872710-11-7
6-[(4-isobutyl-2-methoxybenzyl)oxy]-1-methyl-3,4-dihydro-2-naphthalenecarbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium tetrahydroborate / methanol / 1.5 h / 0 °C

2.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 1 h / 0 - 20 °C

2.2: 4 h / 20 °C

With sodium tetrahydroborate; carbon tetrabromide; triphenylphosphine; In methanol; dichloromethane;
DOI:10.1021/acs.jmedchem.7b00785