tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

Base Information

Chemical Name:tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate
CAS No.:1621273-15-1
Molecular Formula:C₂₅H₂₅F₃N₄O₅S
Molecular Weight:550.559
Hs Code.:

Synonyms:tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

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Chemical Property of tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

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Technology Process of tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

There total 5 articles about tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1621273-13-9
3-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-2-enone

: 1621273-11-7
tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(phenylsulfonyl)methylcarbamate

: 1621273-15-1
tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

Guidance literature:: 3-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-2-enone; With sodium hydride; In 2-methyltetrahydrofuran; mineral oil; for 0.166667h;

tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(phenylsulfonyl)methylcarbamate; In 2-methyltetrahydrofuran; mineral oil; at 20 ℃; for 0.5h;

Reference yield:

: 4248-19-5
tert-butyl carbazate

: 1621273-15-1
tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: formic acid / tetrahydrofuran / 96 h / 20 °C

2.1: sodium hydride / mineral oil; 2-methyltetrahydrofuran / 0.17 h

2.2: 0.5 h / 20 °C

With formic acid; sodium hydride; In tetrahydrofuran; 2-methyltetrahydrofuran; mineral oil;

Reference yield:

: 1161921-93-2
4-formyl-3-(methylsulfonyl)benzonitrile

: 1621273-15-1
tert-butyl (4-cyano-2-(methylsulfonyl)phenyl)(5-oxo-2-(2-(trifluoromethyl)pyridin-4-ylamino)cyclopent-1-enyl)methylcarbamate

Guidance literature:: Multi-step reaction with 2 steps

1.1: formic acid / tetrahydrofuran / 96 h / 20 °C

2.1: sodium hydride / mineral oil; 2-methyltetrahydrofuran / 0.17 h

2.2: 0.5 h / 20 °C

With formic acid; sodium hydride; In tetrahydrofuran; 2-methyltetrahydrofuran; mineral oil;