N-benzylaminomethyldiphenylphosphine oxide

Base Information

• Chemical Name: N-benzylaminomethyldiphenylphosphine oxide
• CAS No.: 167703-41-5
• Molecular Formula: C₂₀H₂₀NOP
• Molecular Weight: 321.359
• Mol file: 167703-41-5.mol

Synonyms:N-benzylaminomethyldiphenylphosphine oxide

Chemical Property of N-benzylaminomethyldiphenylphosphine oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzylaminomethyldiphenylphosphine oxide

There total 5 articles about N-benzylaminomethyldiphenylphosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + Diphenylphosphine oxide (4559-70-0) + benzylamine (100-46-9) → N-benzylaminomethyldiphenylphosphine oxide (167703-41-5)

Guidance literature:

In acetonitrile; at 100 ℃; for 1h; Sealed tube; Microwave irradiation;

DOI:10.3762/bjoc.15.40

Reference yield: 82.0%

N-benzyl-N-diphenylphosphinoylmethylformamide (167703-38-0) → N-benzylaminomethyldiphenylphosphine oxide (167703-41-5)

Guidance literature:

With hydrogenchloride; In ethanol; Heating;

DOI:10.1016/0040-4039(95)00288-N

Reference yield:

Ethyl diphenylphosphinite (719-80-2) → N-benzylaminomethyldiphenylphosphine oxide (167703-41-5)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 1 h / Heating

2: 82 percent / 10percent aq. HCl / ethanol / 0.5 h / Heating

With hydrogenchloride; In ethanol; toluene;

DOI:10.1016/0040-4020(96)00092-0

upstream raw materials:

N-benzyl-N-diphenylphosphinoylmethylformamide

Ethyl diphenylphosphinite

N-benzylformamide

N-Benzyl-N-chloromethyl-formamide

Downstream raw materials:

N-diphenylphosphinoylmethyl-N-benzyl-2-benzoylbenzamide

N-Benzyl-2-bromo-N-(diphenyl-phosphinoylmethyl)-benzamide

(Aminomethyl)diphenylphosphine oxide