4,6-dibenzyloxy-5-acetylpyrimidine

Base Information

• Chemical Name: 4,6-dibenzyloxy-5-acetylpyrimidine
• CAS No.: 98792-84-8
• Molecular Formula: C₂₀H₁₈N₂O₃
• Molecular Weight: 334.375
• Mol file: 98792-84-8.mol

Synonyms:4,6-dibenzyloxy-5-acetylpyrimidine

Chemical Property of 4,6-dibenzyloxy-5-acetylpyrimidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,6-dibenzyloxy-5-acetylpyrimidine

There total 4 articles about 4,6-dibenzyloxy-5-acetylpyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4,6-dibenzyloxy-5-(α-hydroxyethyl)pyrimidine (98792-89-3) → 4,6-dibenzyloxy-5-acetylpyrimidine (98792-84-8)

Guidance literature:

With manganese(IV) oxide; In dichloromethane; for 10h; Ambient temperature;

DOI:10.1007/BF00506674

Reference yield:

4,6-dichloro-5-(α-hydroxyethyl)pyrimidine (60025-05-0) → 4,6-dibenzyloxy-5-acetylpyrimidine (98792-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Na metal / 2.) methylene chloride, R_.T_., 3 h.

2: 93 percent / active MnO₂ / CH₂Cl₂ / 10 h / Ambient temperature

With manganese(IV) oxide; sodium; In dichloromethane;

DOI:10.1007/BF00506674

Reference yield:

benzyl alcohol (100-51-6,185532-71-2) → 4,6-dibenzyloxy-5-acetylpyrimidine (98792-84-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) Na metal / 2.) methylene chloride, R_.T_., 3 h.

2: 93 percent / active MnO₂ / CH₂Cl₂ / 10 h / Ambient temperature

With manganese(IV) oxide; sodium; In dichloromethane;

DOI:10.1007/BF00506674

upstream raw materials:

4,6-dibenzyloxy-5-(α-hydroxyethyl)pyrimidine

1-(4,6-dichloropyrimidine-5-yl)ethane-1-one

benzyl alcohol

4,6-dichloro-5-(α-hydroxyethyl)pyrimidine

Downstream raw materials:

2',4,6-trichloro-6'-phenyl<4',5>bipyrimidine

4,6-dibenzyloxy-5-pyrimidinyl styryl ketone

(E)-1-(4,6-Bis-benzyloxy-pyrimidin-5-yl)-3-phenyl-propenone

4,6-dihydroxy-5-acetylpyrimidine