C₆₀H₇₄N₄O₂₂

Base Information

• Chemical Name: C₆₀H₇₄N₄O₂₂
• CAS No.: 158008-51-6
• Molecular Formula: C₆₀H₇₄N₄O₂₂
• Molecular Weight: 1203.26
• Mol file: 158008-51-6.mol

Synonyms:C₆₀H₇₄N₄O₂₂

Chemical Property of C₆₀H₇₄N₄O₂₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₆₀H₇₄N₄O₂₂

There total 5 articles about C₆₀H₇₄N₄O₂₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(2S,3S,4R,5R,6S)-2-Bromo-3,4,5-tris-(4-methoxy-benzyloxy)-6-methyl-tetrahydro-pyran + Acetic acid (2S,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(2R,3S,4R,5R,6R)-5-acetylamino-6-azido-4-hydroxy-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-3-yl ester (158008-50-5) → C60H74N4O22 (158008-51-6)

Guidance literature:

With 2,6-di-tert-butyl-pyridine; tetraethylammonium bromide; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

azido 4,6-O-(4-methoxybenzylidene)-2-deoxy-2-acetamido-β-D-glucopyranoside → C60H74N4O22 (158008-51-6)

Guidance literature:

Multi-step reaction with 5 steps

1: Ba(OH)2 / dimethylformamide

2: NaCNBH₃, CF₃COOH / dimethylformamide

3: 78 percent / AgOTf, 2,6-di-tert-butylpyridine / CH₂Cl₂; toluene

4: 55 percent / PdCl₂, NaOAc / acetic acid / 50 °C

5: 90 percent / Et₄NBr, 2,6-di-tert-butylpyridine / CH₂Cl₂; dimethylformamide

With barium dihydroxide; 2,6-di-tert-butyl-pyridine; tetraethylammonium bromide; sodium acetate; silver trifluoromethanesulfonate; sodium cyanoborohydride; trifluoroacetic acid; palladium dichloride; In dichloromethane; acetic acid; N,N-dimethyl-formamide; toluene;

Reference yield:

N-[(2R,4aR,6R,7R,8R,8aS)-8-Allyloxy-6-azido-2-(4-methoxy-phenyl)-hexahydro-pyrano[3,2-d][1,3]dioxin-7-yl]-acetamide → C60H74N4O22 (158008-51-6)

Guidance literature:

Multi-step reaction with 4 steps

1: NaCNBH₃, CF₃COOH / dimethylformamide

2: 78 percent / AgOTf, 2,6-di-tert-butylpyridine / CH₂Cl₂; toluene

3: 55 percent / PdCl₂, NaOAc / acetic acid / 50 °C

4: 90 percent / Et₄NBr, 2,6-di-tert-butylpyridine / CH₂Cl₂; dimethylformamide

With 2,6-di-tert-butyl-pyridine; tetraethylammonium bromide; sodium acetate; silver trifluoromethanesulfonate; sodium cyanoborohydride; trifluoroacetic acid; palladium dichloride; In dichloromethane; acetic acid; N,N-dimethyl-formamide; toluene;

upstream raw materials:

Acetic acid (2S,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(2R,3S,4R,5R,6R)-5-acetylamino-6-azido-4-hydroxy-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-3-yl ester

N-[(2R,3R,4R,5S,6R)-4-Allyloxy-2-azido-5-hydroxy-6-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yl]-acetamide

Acetic acid (2S,3R,4S,5S,6R)-4,5-diacetoxy-6-acetoxymethyl-2-[(2R,3S,4R,5R,6R)-5-acetylamino-4-allyloxy-6-azido-2-(4-methoxy-benzyloxymethyl)-tetrahydro-pyran-3-yloxy]-tetrahydro-pyran-3-yl ester