4-tritylphenyl 10-bromodeca-5,7,9-triynoate

Base Information

• Chemical Name: 4-tritylphenyl 10-bromodeca-5,7,9-triynoate
• CAS No.: 1426234-06-1
• Molecular Formula: C₃₅H₂₅BrO₂
• Molecular Weight: 557.486
• Mol file: 1426234-06-1.mol

Synonyms:4-tritylphenyl 10-bromodeca-5,7,9-triynoate

Chemical Property of 4-tritylphenyl 10-bromodeca-5,7,9-triynoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-tritylphenyl 10-bromodeca-5,7,9-triynoate

There total 3 articles about 4-tritylphenyl 10-bromodeca-5,7,9-triynoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-tritylphenyl 10-(trimethylsilyl)deca-5,7,9-triynoate (1426234-05-0) → 4-tritylphenyl 10-bromodeca-5,7,9-triynoate (1426234-06-1)

Guidance literature:

With N-Bromosuccinimide; silver fluoride; In dichloromethane; acetonitrile; at 20 ℃; for 6h; Darkness;

DOI:10.1038/nchem.1575

Reference yield:

C31H26O2 → 4-tritylphenyl 10-bromodeca-5,7,9-triynoate (1426234-06-1)

Guidance literature:

Multi-step reaction with 3 steps

1: silver nitrate; N-Bromosuccinimide / acetonitrile; dichloromethane

2: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / tetrahydrofuran; toluene

3: N-Bromosuccinimide; silver fluoride / dichloromethane

With N-Bromosuccinimide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; silver fluoride; silver nitrate; In tetrahydrofuran; dichloromethane; toluene; acetonitrile; 2: |Negishi Coupling;

DOI:10.1039/c4sc03154g

Reference yield:

C31H25BrO2 → 4-tritylphenyl 10-bromodeca-5,7,9-triynoate (1426234-06-1)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂ / tetrahydrofuran; toluene

2: N-Bromosuccinimide; silver fluoride / dichloromethane

With N-Bromosuccinimide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; silver fluoride; In tetrahydrofuran; dichloromethane; toluene; 1: |Negishi Coupling;

DOI:10.1039/c4sc03154g

upstream raw materials:

4-tritylphenyl 10-(trimethylsilyl)deca-5,7,9-triynoate

Downstream raw materials:

(E)-9,10-dibromoicosa-9-ene-5,7,11,13,15-pentaynedioic acid bis(4-tritylphenyl)ester