(2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan

Base Information

• Chemical Name: (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan
• CAS No.: 110237-87-1
• Molecular Formula: C₂₇H₂₈O₄
• Molecular Weight: 416.517
• Mol file: 110237-87-1.mol

Synonyms:(2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan

Chemical Property of (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan

There total 2 articles about (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

(3aR,5R,6S,6aR)-6-Benzyloxy-5-((R)-1,2-bis-benzyloxy-ethyl)-tetrahydro-furo[2,3-d][1,3]dioxole-2-thione → (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan (110237-87-1)

Guidance literature:

With 1,3-dimethyl-2-phenyldiazaphospholidine; In toluene; at 70 ℃;

DOI:10.1016/S0008-6215(97)00072-4

Reference yield: 50.0%

3,5,6-Tri-O-benzyl-α,β-D-glucofuranose (35958-64-6,81969-62-2,81969-65-5,114180-97-1,114180-98-2) → (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan (110237-87-1)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In dichloromethane;

DOI:10.1016/S0008-6215(97)00072-4

Reference yield: 88.0%

acetonitrile (75-05-8,26809-02-9) + (2S,3R)-3-Benzyloxy-2-((R)-1,2-bis-benzyloxy-ethyl)-2,3-dihydro-furan (110237-87-1) → C29H32ClNO5 (1000844-97-2)

Guidance literature:

With oxalyl dichloride; silver nitrate; cooling;

DOI:10.1021/ol702097q

upstream raw materials:

3,5,6-Tri-O-benzyl-α,β-D-glucofuranose

Downstream raw materials:

C₂₉H₃₂ClNO₅