Technology Process of N-dodecyl-2,5-diphenyl-3,4-(propylene-1,3-dioxy)pyrrole
There total 5 articles about N-dodecyl-2,5-diphenyl-3,4-(propylene-1,3-dioxy)pyrrole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis(acetylacetonato)palladium(II); tetrabutylammomium bromide; tris-(o-tolyl)phosphine;
In
1-methyl-pyrrolidin-2-one;
at 70 - 75 ℃;
for 36h;
Inert atmosphere;
DOI:10.1021/jo201770j
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium hydroxide / tetrahydrofuran; ethanol; water / 36 h / 75 °C / Inert atmosphere
1.2: Inert atmosphere; Cooling with ice
2.1: potassium tert-butylate / tetrahydrofuran; tert-butyl alcohol / 0.5 h / Inert atmosphere
3.1: bis(acetylacetonato)palladium(II); tetrabutylammomium bromide; tris-(o-tolyl)phosphine / 1-methyl-pyrrolidin-2-one / 36 h / 70 - 75 °C / Inert atmosphere
With
bis(acetylacetonato)palladium(II); potassium tert-butylate; tetrabutylammomium bromide; tris-(o-tolyl)phosphine; potassium hydroxide;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; ethanol; water; tert-butyl alcohol;
DOI:10.1021/jo201770j
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 95 °C / Inert atmosphere
2.1: potassium hydroxide / tetrahydrofuran; ethanol; water / 36 h / 75 °C / Inert atmosphere
2.2: Inert atmosphere; Cooling with ice
3.1: potassium tert-butylate / tetrahydrofuran; tert-butyl alcohol / 0.5 h / Inert atmosphere
4.1: bis(acetylacetonato)palladium(II); tetrabutylammomium bromide; tris-(o-tolyl)phosphine / 1-methyl-pyrrolidin-2-one / 36 h / 70 - 75 °C / Inert atmosphere
With
bis(acetylacetonato)palladium(II); potassium tert-butylate; tetrabutylammomium bromide; potassium carbonate; tris-(o-tolyl)phosphine; potassium hydroxide;
In
tetrahydrofuran; 1-methyl-pyrrolidin-2-one; ethanol; water; N,N-dimethyl-formamide; tert-butyl alcohol;
DOI:10.1021/jo201770j
