10-propargyl-5-deazafolic acid

Base Information

• Chemical Name: 10-propargyl-5-deazafolic acid
• CAS No.: 115722-29-7
• Molecular Formula: C23H22 N6 O6
• Molecular Weight: 478.464
• Mol file: 115722-29-7.mol

Synonyms:Pyrido[2,3-d]pyrimidine,L-glutamic acid deriv.

Chemical Property of 10-propargyl-5-deazafolic acid

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 192.59000
• Density: 1.46g/cm³
• LogP: 1.32120

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 10-propargyl-5-deazafolic acid

There total 1 articles about 10-propargyl-5-deazafolic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

10-propargyl-5-deazafolic acid diethyl ester (138286-62-1) → 10-propargyl-5-deazafolic acid (115722-29-7)

Guidance literature:

With sodium hydroxide; In methanol; at 20 - 25 ℃; for 20h;

DOI:10.1021/jm00080a019

upstream raw materials:

10-propargyl-5-deazafolic acid diethyl ester