Technology Process of C28H32O3Si
There total 4 articles about C28H32O3Si which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diethoxyphosphoryl-acetic acid ethyl ester;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.25h;
Inert atmosphere;
2-(tert-Butyl-diphenyl-silanyloxymethyl)-benzaldehyde;
With
4-hydroxymethyl-3-methoxyphenoxyacetic acid;
In
tetrahydrofuran; hexane;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1039/c1cc14269k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C / Inert atmosphere
2.1: silica gel; pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
3.2: -78 - 20 °C / Inert atmosphere
With
n-butyllithium; silica gel; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate;
In
tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c1cc14269k
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Cooling with ice
2.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C / Inert atmosphere
3.1: silica gel; pyridinium chlorochromate / dichloromethane / 3 h / 20 °C / Inert atmosphere
4.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere
4.2: -78 - 20 °C / Inert atmosphere
With
lithium aluminium tetrahydride; n-butyllithium; silica gel; N-ethyl-N,N-diisopropylamine; pyridinium chlorochromate;
In
tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c1cc14269k
