(2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran

Base Information

• Chemical Name: (2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran
• CAS No.: 1058728-79-2
• Molecular Formula: C₂₂H₃₂O₄
• Molecular Weight: 360.494
• Mol file: 1058728-79-2.mol

Synonyms:(2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran

Chemical Property of (2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran

There total 1 articles about (2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(2S,3S)-2-allyloxy-hex-5-en-3-ol (1058728-65-6) + (3S,2S)-3-benzyloxy-2-methyl-3,4-dihydro-2H-pyran (187410-80-6) → (2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran (1058728-79-2)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; for 12h; Inert atmosphere;

DOI:10.1002/chem.200800567

Reference yield: 75.0%

(2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran (1058728-79-2) → (2S,3S)-3-((2S,5S,6S)-5-benzyloxy-6-methyltetrahydropyran-2-yloxy)-2-methyl-2,3,4,5-tetrahydrooxepine (1058728-81-6)

Guidance literature:

(2S,3S,6S)-6-[((1S,2S)-allyloxyethyl)-but-3-enyloxy]-3-benzyloxy-2-methyltetrahydropyran; With Grubbs catalyst first generation; In toluene; at 20 ℃; Inert atmosphere;

With sodium hydroxide; isopropyl alcohol; In toluene; at 110 ℃; Inert atmosphere;

DOI:10.1002/chem.200800567

upstream raw materials:

(2S,3S)-2-allyloxy-hex-5-en-3-ol

(3S,2S)-3-benzyloxy-2-methyl-3,4-dihydro-2H-pyran

Downstream raw materials:

(2S,3S)-3-((2S,5S,6S)-5-benzyloxy-6-methyltetrahydropyran-2-yloxy)-2-methyl-2,3,4,5-tetrahydrooxepine