2,3-Dihydroxyquinoxaline

Base Information

• Chemical Name: 2,3-Dihydroxyquinoxaline
• CAS No.: 15804-19-0
• Deprecated CAS: 6287-20-3
• Molecular Formula: C8H6 N2 O2
• Molecular Weight: 162.148
• Hs Code.: 29339900
• European Community (EC) Number: 239-901-0
• NSC Number: 9431,8698
• UNII: APO55IZ9E1
• DSSTox Substance ID: DTXSID9065946
• Nikkaji Number: J48.373G
• Wikidata: Q21099569
• ChEMBL ID: CHEMBL282672
• Mol file: 15804-19-0.mol

Synonyms:2,3-dihydroxyquinoxaline

Chemical Property of 2,3-Dihydroxyquinoxaline

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: >300 °C(lit.)
• Refractive Index: 1.762
• Boiling Point: 470.9°Cat760mmHg
• PKA: 10.66±0.20(Predicted)
• Flash Point: 238.6°C
• PSA: 65.72000
• Density: 1.336g/cm³
• LogP: 0.21640
• Storage Temp.: 2-8°C
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 162.042927438
• Heavy Atom Count: 12
• Complexity: 203

Purity/Quality:

98%, ^*data from raw suppliers

1,4-Dihydroquinoxaline-2,3-dione ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 22-24/25-39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Rings
• Canonical SMILES: C1=CC=C2C(=C1)NC(=O)C(=O)N2

Technology Process of 2,3-Dihydroxyquinoxaline

There total 74 articles about 2,3-Dihydroxyquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

oxalic acid (144-62-7,97993-78-7) + 1,2-diamino-benzene (95-54-5) → quinoxaline-2,3-dione (15804-19-0,6287-20-3)

Guidance literature:

at 150 ℃; for 8h; Further Variations:; Temperatures; Product distribution; solid-state reaction;

DOI:10.1002/1099-0690(200204)2002:8<1368::AID-EJOC1368>3.0.CO;2-6

Reference yield: 93.0%

ethyl (2E)-(3-oxo-3,4-dihydroquinoxalin-2(1H)-ylidene)ethanoate (30681-63-1,86482-20-4) → quinoxaline-2,3-dione (15804-19-0,6287-20-3)

Guidance literature:

With peracetic acid; In water; at 50 ℃; for 8h;

Reference yield: 91.0%

quinoxalin-2(1)-one (1196-57-2) → quinoxaline-2,3-dione (15804-19-0,6287-20-3)

Guidance literature:

With ammonium peroxydisulfate; In water; acetonitrile; at 60 ℃;

upstream raw materials:

2,3-diethynylquinoxaline

quinoxalin-2⁽¹⁾-one

2-(methylthio)quinoxaline

2-mercapto-3-hydrazinoquinoxaline

Downstream raw materials:

C₈H₆N₂S₂

C₂₁H₁₇N₃O₂

1,4-dimethylquinoxaline-2,3(1H,4H)-dione

C₂₆H₂₂N₂O₆