C₇₆H₁₀₄N₈O₁₁

Base Information

• Chemical Name: C₇₆H₁₀₄N₈O₁₁
• CAS No.: 1402450-99-0
• Molecular Formula: C₇₆H₁₀₄N₈O₁₁
• Molecular Weight: 1305.71
• Mol file: 1402450-99-0.mol

Synonyms:C₇₆H₁₀₄N₈O₁₁

Chemical Property of C₇₆H₁₀₄N₈O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₇₆H₁₀₄N₈O₁₁

There total 8 articles about C₇₆H₁₀₄N₈O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

C25H39N3O6 (1402451-07-3) + C2HF3O2*C51H67N5O6 (1402451-14-2) → C76H104N8O11 (1402450-99-0)

Guidance literature:

C₂₅H₃₉N₃O₆; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; at 0 ℃; for 0.166667h; Inert atmosphere;

C₂HF₃O₂*C₅₁H₆₇N₅O₆; In N,N-dimethyl-formamide; at 20 ℃; for 120h; Inert atmosphere;

DOI:10.1002/chem.201201415

Reference yield:

C17H25NO4 (1402451-00-6) → C76H104N8O11 (1402450-99-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

4.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

5.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

5.2: 120 h / 20 °C / Inert atmosphere

With palladium 10% on activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; In methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.201201415

Reference yield:

C2HF3O2*C19H23NO2 (1402451-03-9) → C76H104N8O11 (1402450-99-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere

2.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

3.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

4.1: dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere

5.1: N-ethyl-N,N-diisopropylamine; HATU / N,N-dimethyl-formamide / 0.17 h / 0 °C / Inert atmosphere

5.2: 120 h / 20 °C / Inert atmosphere

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1002/chem.201201415

upstream raw materials:

C₂₈H₃₈N₂O₅

C₂₁H₃₂N₂O₅

C₄₀H₅₃N₃O₆

C₁₇H₂₅NO₄