2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione

Base Information

• Chemical Name: 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione
• CAS No.: 1364664-23-2
• Molecular Formula: C₁₆H₁₃N₃O₂S
• Molecular Weight: 311.364
• Mol file: 1364664-23-2.mol

Synonyms:2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione

Chemical Property of 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione

There total 3 articles about 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinone (740-37-4) → 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione (1364664-23-2)

Guidance literature:

With tetraphosphorus decasulfide; In 5,5-dimethyl-1,3-cyclohexadiene; for 12h; Reflux;

DOI:10.1016/j.bmcl.2012.01.071

Reference yield:

o-toluidine (95-53-4) → 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione (1364664-23-2)

Guidance literature:

Multi-step reaction with 2 steps

2: tetraphosphorus decasulfide / 5,5-dimethyl-1,3-cyclohexadiene / 12 h / Reflux

With tetraphosphorus decasulfide; In 5,5-dimethyl-1,3-cyclohexadiene;

DOI:10.1016/j.bmcl.2012.01.071

Reference yield:

4-Nitroanthranilic acid (619-17-0) → 2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinthione (1364664-23-2)

Guidance literature:

Multi-step reaction with 2 steps

2: tetraphosphorus decasulfide / 5,5-dimethyl-1,3-cyclohexadiene / 12 h / Reflux

With tetraphosphorus decasulfide; In 5,5-dimethyl-1,3-cyclohexadiene;

DOI:10.1016/j.bmcl.2012.01.071

upstream raw materials:

2-methyl-3-(2-methylphenyl)-7-nitro-4(3H)-quinazolinone

o-toluidine

4-Nitroanthranilic acid

Downstream raw materials:

2-methyl-3-(2-methylphenyl)-7-amino-4(3H)-quinazolinthione