Technology Process of 1,2-dibromo-3-benzyloxy-4,6-dimethoxybenzene
There total 7 articles about 1,2-dibromo-3-benzyloxy-4,6-dimethoxybenzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
N-Bromosuccinimide; ammonium acetate;
In
acetonitrile;
at 20 ℃;
for 1.5h;
Inert atmosphere;
DOI:10.1039/c9ob01221d
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 90 percent / potassium carbonate / dimethylformamide / 5 h / 80 °C
2: m-chloroperbenzoic acid / CH2Cl2 / 4 h / Heating
3: 12.4 g / potassium hydroxide / H2O / 18 h / 25 °C
4: 78 percent / potassium carbonate / acetone / 18 h / Heating
5: 90 percent / bromine; acetic acid; sodium acetate / 0.25 h / 25 °C
With
potassium hydroxide; bromine; sodium acetate; potassium carbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; water; N,N-dimethyl-formamide; acetone;
2: Baeyer-Villiger oxidation;
DOI:10.1080/00397910600616693
- Guidance literature:
-
Multi-step reaction with 4 steps
1: m-chloroperbenzoic acid / CH2Cl2 / 4 h / Heating
2: 12.4 g / potassium hydroxide / H2O / 18 h / 25 °C
3: 78 percent / potassium carbonate / acetone / 18 h / Heating
4: 90 percent / bromine; acetic acid; sodium acetate / 0.25 h / 25 °C
With
potassium hydroxide; bromine; sodium acetate; potassium carbonate; acetic acid; 3-chloro-benzenecarboperoxoic acid;
In
dichloromethane; water; acetone;
1: Baeyer-Villiger oxidation;
DOI:10.1080/00397910600616693
