phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

Base Information

Chemical Name:phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate
CAS No.:164584-74-1
Molecular Formula:C₂₆H₂₁N₃O₃
Molecular Weight:423.471
Hs Code.:

Synonyms:phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

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Chemical Property of phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

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Technology Process of phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

There total 4 articles about phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 164584-73-0
ethyl 1-ethyl-1,4-dihydro-4-<<2-oxo-2-(phenylmethoxy)ethyl>imino>-7-(4-pyridinyl)-3-quinolinecarboxylate

: 164584-74-1
phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

Guidance literature:: With triethylamine; In chloroform; for 168h; Heating;
DOI:10.1021/jm00014a006

Reference yield:

: 164584-71-8
ethyl 1-ethyl-1,4-dihydro-7-(4-pyridinyl)-4-thioxo-3-quinolinecarboxylate

: 164584-74-1
phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / tetrahydrofuran / 21 h / 25 °C

2: 52 percent / pyridine / 18 h / 25 °C

3: 91 percent / Et₃N / CHCl₃ / 168 h / Heating

With pyridine; triethylamine; In tetrahydrofuran; chloroform;
DOI:10.1021/jm00014a006

Reference yield:

: ethyl 1-ethyl-7-(4-pyridinyl)-4-(methylthio)-3-quinoliniumcarboxylate iodide

: 164584-74-1
phenylmethyl 5-ethyl-3-hydroxy-7-(4-pyridinyl)-5H-pyrrolo<3,2-c>quinoline-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / pyridine / 18 h / 25 °C

2: 91 percent / Et₃N / CHCl₃ / 168 h / Heating

With pyridine; triethylamine; In chloroform;
DOI:10.1021/jm00014a006