1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

Base Information

Chemical Name:1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde
CAS No.:162512-51-8
Molecular Formula:C₂₅H₂₂N₂O₂
Molecular Weight:382.462
Hs Code.:

Synonyms:1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

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Technology Process of 1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

There total 1 articles about 1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 162512-51-8
1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

Guidance literature:

Reference yield: 71.0%

: 162512-51-8
1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

: 162512-92-7
1-(4-Fluorophenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-methanol

Guidance literature:: With sodium tetrahydroborate; In ethanol; dichloromethane;
DOI:10.1016/S0960-894X(97)10016-6

Reference yield:

: 162512-51-8
1-(4-Hydroxyphenyl)-7-[(1-naphthyl)methyl]-4,5,6,7-tetrahydro-1H-indazole-3-carboxaldehyde

: Benzoic acid 1-(4-fluoro-phenyl)-7-naphthalen-1-ylmethyl-4,5,6,7-tetrahydro-1H-indazol-3-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol; dichloromethane

2: pyridine; dichloromethane

With sodium tetrahydroborate; In pyridine; ethanol; dichloromethane;
DOI:10.1016/S0960-894X(97)10016-6