Technology Process of PALLASONE B
There total 5 articles about PALLASONE B which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
disodium hydrogen phosphate monohydrate; potassium nitrososulfonate; Aliquat 336;
In
dichloromethane; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 65 percent / tetrahydrofuran / 2 h / 0 °C
2: 74 percent / triphenylphosphine; diisopropyl azodicarboxylate / toluene / 24 h / 20 °C
3: 92 percent / dimethylformamide / 0.5 h / 180 °C / microwave irradiation
4: 85 percent / H2 / Pd/C / ethyl acetate / 4 h
5: 48 percent / salcomine catalyst; O2 / acetonitrile / 24 h / 20 °C
With
di-isopropyl azodicarboxylate; salcomine catalyst; hydrogen; oxygen; triphenylphosphine;
palladium on activated charcoal;
In
tetrahydrofuran; ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile;
2: Mitsunobu reaction / 3: Claisen rearrangement;
DOI:10.1021/jo050336x
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 74 percent / triphenylphosphine; diisopropyl azodicarboxylate / toluene / 24 h / 20 °C
2: 92 percent / dimethylformamide / 0.5 h / 180 °C / microwave irradiation
3: 85 percent / H2 / Pd/C / ethyl acetate / 4 h
4: 48 percent / salcomine catalyst; O2 / acetonitrile / 24 h / 20 °C
With
di-isopropyl azodicarboxylate; salcomine catalyst; hydrogen; oxygen; triphenylphosphine;
palladium on activated charcoal;
In
ethyl acetate; N,N-dimethyl-formamide; toluene; acetonitrile;
1: Mitsunobu reaction / 2: Claisen rearrangement;
DOI:10.1021/jo050336x
