1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine

Base Information

Chemical Name:1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine
CAS No.:200052-11-5
Molecular Formula:C₁₅H₁₅F₃N₂O₄
Molecular Weight:344.29
Hs Code.:

Synonyms:1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine

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Chemical Property of 1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine

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Technology Process of 1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine

There total 2 articles about 1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: O-methylisourea hydrogen hemisulfate

: Methyl 2-methoxyacetyl-3-(2,3,6-trifluorophenyl)acrylate

: 200052-11-5
1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine

Guidance literature:: With dmap; In ethanol;

Reference yield:

: 104451-70-9
2,3,6-trifluorobenzaldehyde

: 200052-11-5
1,6-dihydro-2-methoxy-5-methoxycarbonyl-4-methoxymethyl-6-(2,3,6-trifluorophenyl)pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: piperdinium acetate / benzene

2: dmap / ethanol

With dmap; piperdinium acetate; In ethanol; benzene;