Technology Process of dibenzyl 1-((2S,3S,4R)-1,2,3,8-tetrahydroxyoctan-4-yl)hydrazine-1,2-dicarboxylate
There total 5 articles about dibenzyl 1-((2S,3S,4R)-1,2,3,8-tetrahydroxyoctan-4-yl)hydrazine-1,2-dicarboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
lithium borohydride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 2h;
DOI:10.1039/c4ob00461b
- Guidance literature:
-
Multi-step reaction with 4 steps
1: L-proline
2: 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride / acetonitrile
3: osmium(VIII) oxide; potassium hexacyanoferrate(III); potassium carbonate; hydroquinine (anthraquinone-1,4-diyl) diether; methanesulfonamide / tert-butyl alcohol; water; toluene / 24 h / 0 °C
4: lithium borohydride / tetrahydrofuran / 2 h / 0 - 20 °C
With
osmium(VIII) oxide; lithium borohydride; hydroquinine (anthraquinone-1,4-diyl) diether; methanesulfonamide; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; L-proline; lithium chloride; potassium hexacyanoferrate(III);
In
tetrahydrofuran; water; toluene; acetonitrile; tert-butyl alcohol;
2: |Horner-Wadsworth-Emmons Olefination / 3: |Sharpless Dihydroxylation;
DOI:10.1039/c4ob00461b
- Guidance literature:
-
Multi-step reaction with 2 steps
1: osmium(VIII) oxide; potassium hexacyanoferrate(III); potassium carbonate; hydroquinine (anthraquinone-1,4-diyl) diether; methanesulfonamide / tert-butyl alcohol; water; toluene / 24 h / 0 °C
2: lithium borohydride / tetrahydrofuran / 2 h / 0 - 20 °C
With
osmium(VIII) oxide; lithium borohydride; hydroquinine (anthraquinone-1,4-diyl) diether; methanesulfonamide; potassium carbonate; potassium hexacyanoferrate(III);
In
tetrahydrofuran; water; toluene; tert-butyl alcohol;
1: |Sharpless Dihydroxylation;
DOI:10.1039/c4ob00461b