(E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

Base Information

Chemical Name:(E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene
CAS No.:129812-69-7
Molecular Formula:C₂₁H₁₇ClN₂O₂
Molecular Weight:364.831
Hs Code.:

Synonyms:(E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

Suppliers and Price of (E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

There total 1 articles about (E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 129812-68-6
(E)-1-(6-carbethoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

: 100-51-6,185532-71-2
benzyl alcohol

: 129812-69-7
(E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

Guidance literature:: With sodium phenyl-methanolate; at 80 ℃; for 4h;
DOI:10.1021/jo00313a016

Reference yield:

: 129812-69-7
(E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

: N^α-(tert-butoxycarbonyl)-N^β-<1-ethoxy-3-(4-azido-6-carbobenzoxy-5-methylpyrimidin-2-yl)propion-3-yl>-(S)-β-aminoalanineamide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) ozone, 2.) dimethyl sulfide / 1.) CHCl₃, CH₂Cl₂, -78 deg C, 2.) 25 deg C, 14 h

2: 81 percent / 3-Angstroem molecular sieves / acetonitrile / 24 h / 25 °C

3: 14 percent / benzene / 24 h / 42 °C

4: 100 percent / NaN₃ / dimethylformamide / 4 h / 0 °C

With sodium azide; dimethylsulfide; 3 A molecular sieve; ozone; In N,N-dimethyl-formamide; acetonitrile; benzene;
DOI:10.1021/jo00313a016

Reference yield:

: 129812-69-7
(E)-1-(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)-2-phenylethylene

: 129812-71-1
N^α-(tert-butoxycarbonyl)-N^β-<<(6-carbobenzoxy-4-chloro-5-methylpyrimidin-2-yl)methylene>amino>-(S)-β-aminoalanineamide

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) ozone, 2.) dimethyl sulfide / 1.) CHCl₃, CH₂Cl₂, -78 deg C, 2.) 25 deg C, 14 h

2: 81 percent / 3-Angstroem molecular sieves / acetonitrile / 24 h / 25 °C

With dimethylsulfide; 3 A molecular sieve; ozone; In acetonitrile;
DOI:10.1021/jo00313a016