(2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate

Base Information

• Chemical Name: (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate
• CAS No.: 1382355-14-7
• Molecular Formula: C₇H₇O₃S*C₁₆H₁₆FINO
• Molecular Weight: 555.409
• Mol file: 1382355-14-7.mol

Synonyms:(2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate

Chemical Property of (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate

There total 4 articles about (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluoro-1-iodobenzene (352-34-1) → (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate (1382355-14-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium periodate; acetic anhydride / acetic acid / 2 h / 120 °C

2: dichloromethane; acetonitrile / 1 h / 20 °C / Inert atmosphere

3: dichloromethane; acetonitrile / 24 h / 20 °C / Inert atmosphere

With sodium periodate; acetic anhydride; In dichloromethane; acetic acid; acetonitrile;

DOI:10.1021/jo300874m

Reference yield:

2-(trimethylstannylphenyl)ethylacetamide (1382354-91-7) + (4-fluorophenyl)(hydroxy)-λ3-iodaneyl 4-methylbenzenesulfonate (84383-77-7) → (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate (1382355-14-7)

Guidance literature:

In dichloromethane; acetonitrile; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1021/jo300874m

Reference yield:

(4-fluorophenyl)-λ3-iodanediyl diacetate (16308-15-9) → (2-(2-acetamidoethyl)phenyl)(4-fluorophenyl)iodonium p-toluenesulfonate (1382355-14-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane; acetonitrile / 1 h / 20 °C / Inert atmosphere

2: dichloromethane; acetonitrile / 24 h / 20 °C / Inert atmosphere

In dichloromethane; acetonitrile;

DOI:10.1021/jo300874m

upstream raw materials:

2-(trimethylstannylphenyl)ethylacetamide

(4-fluorophenyl)(hydroxy)-λ3-iodaneyl 4-methylbenzenesulfonate

4-fluoro-1-iodobenzene

(4-fluorophenyl)-λ³-iodanediyl diacetate

Downstream raw materials:

1-Acetyl-2,3-dihydro-1H-indole