ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Base Information

Chemical Name:ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide
CAS No.:865300-51-2
Molecular Formula:C₁₈H₁₆ClFN₂O₅
Molecular Weight:394.787
Hs Code.:

Synonyms:ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Suppliers and Price of ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

There total 6 articles about ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 865300-50-1
ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate

: 865300-51-2
ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Guidance literature:: With dihydrogen peroxide; acetic acid; In water; at 100 ℃; for 4h;

Reference yield:

: 865300-49-8
1-(3-chloro-4-fluorobenzyl)piperidin-2-one

: 865300-51-2
ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Guidance literature:: Multi-step reaction with 3 steps

1.1: lithium hexamethyldisilazane / tetrahydrofuran / 3.33 h / -20 °C

2.1: water / 72 h / 0 - 135 °C

3.1: dihydrogen peroxide; acetic acid / water / 4 h / 100 °C

3.2: 0 - 40 °C

With water; dihydrogen peroxide; acetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; water;

Reference yield:

: 865300-22-7
butyl N-[ethoxy(oxo)acetyl]glycinate

: 865300-51-2
ethyl 6-(3-chloro-4-fluorobenzyl)-4-hydroxy-5-oxo-5,6,7,8-tetrahydro-2,6-naphthyridine-1-carboxylate 2-oxide

Guidance literature:: Multi-step reaction with 3 steps

1.1: phosphorus pentoxide / water; acetonitrile / 1 h / 20 - 60 °C

2.1: water / 72 h / 0 - 135 °C

3.1: dihydrogen peroxide; acetic acid / water / 4 h / 100 °C

3.2: 0 - 40 °C

With water; dihydrogen peroxide; phosphorus pentoxide; acetic acid; In water; acetonitrile;