ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate

Base Information

• Chemical Name: ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate
• CAS No.: 911196-32-2
• Molecular Formula: C₁₉H₂₉NO₆
• Molecular Weight: 367.442
• Mol file: 911196-32-2.mol

Synonyms:ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate

Chemical Property of ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate

There total 1 articles about ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

Ethyl 4-bromobutyrate (2969-81-5) + tert-butyl (2-hydroxy-2-(4-hydroxyphenyl)ethyl)carbamate (126395-31-1) → ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate (911196-32-2)

Guidance literature:

With potassium carbonate; In acetonitrile; Heating / reflux;

Reference yield: 83.0%

ethyl 4-{4-[2-(t-butylcarboxamido)-1-hydroxyethyl]phenoxy}butanoate (911196-32-2) + trifluoroacetic acid (76-05-1) → ethyl 4-[4-(2-amino-1-hydroxyethyl)phenoxy]butanoate trifluoroacetate

Guidance literature:

In dichloromethane; at 20 ℃; for 1h;

upstream raw materials:

Ethyl 4-bromobutyrate

tert-butyl (2-hydroxy-2-(4-hydroxyphenyl)ethyl)carbamate