(-)-(S)-4,4-dimethylcyclohex-2-en-1-ol

Base Information

• Chemical Name: (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol
• CAS No.: 71687-74-6
• Molecular Formula: C₈H₁₄O
• Molecular Weight: 126.199
• Mol file: 71687-74-6.mol

Synonyms:(-)-(S)-4,4-dimethylcyclohex-2-en-1-ol

Chemical Property of (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol

There total 6 articles about (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

(S)-2-iodo-4,4-dimethyl-2-cyclohexen-1-ol → (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol (71687-74-6)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; triethylamine; In methanol; at 20 ℃; for 1h;

DOI:10.1016/j.tet.2016.08.078

Reference yield:

4,4-dimethylcyclohex-2-en-1-yl acetate (1239277-52-1) → (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol (71687-74-6)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃; optical yield given as %ee;

DOI:10.1016/j.tetasy.2010.02.031

Reference yield:

vinyl acetate (108-05-4,9003-20-7) + 4,4-dimethyl-2-cyclohexen-1-ol (5020-09-7) → 4,4-dimethylcyclohex-2-en-1-ol (1239277-51-0) + 4,4-dimethylcyclohex-2-en-1-yl acetate (1239277-52-1) + (-)-(S)-4,4-dimethylcyclohex-2-en-1-ol (71687-74-6)

Guidance literature:

vinyl acetate; 4,4-dimethyl-2-cyclohexen-1-ol; With Lipase Amano PS; In hexane; at 20 ℃; for 96h; Enzymatic reaction;

With Lipase Amano PS; for 120h; pH=7; aq. phosphate buffer; Enzymatic reaction;

vinyl acetate; With Candida cylindracea lipase; In hexane; for 120h; Enzymatic reaction;

DOI:10.1016/j.tetasy.2010.02.031

upstream raw materials:

vinyl acetate

4,4-dimethyl-2-cyclohexen-1-ol

4,4-dimethylcyclohex-2-en-1-yl acetate

2-iodo-4,4-dimethyl-cyclohex-2-enone