allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate

Base Information

• Chemical Name: allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate
• CAS No.: 916843-45-3
• Molecular Formula: C₂₄H₂₆F₃NO₆S
• Molecular Weight: 513.535

Synonyms:allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate

Chemical Property of allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate

There total 2 articles about allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-ol (916843-42-0) + prop-2-en-1-yl (4-methylbenzene-1-sulfonyl)carbamate (18303-03-2) → allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate (916843-45-3)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene; at 20 ℃; for 12h;

DOI:10.1021/jo061421n

Reference yield:

2,4-Dimethoxybenzaldehyde (613-45-6) → allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate (916843-45-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 63 percent / TBAF / tetrahydrofuran / 24 h / 20 °C

2: 67 percent / DEAD; PPh₃ / tetrahydrofuran; toluene / 12 h / 20 °C

With tetrabutyl ammonium fluoride; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; toluene;

DOI:10.1021/jo061421n

Reference yield: 93.0%

allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate (916843-45-3) → N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-4-methylbenzenesulfonamide (916843-47-5)

Guidance literature:

With piperidine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In acetonitrile; at 20 ℃; for 12h;

DOI:10.1021/jo061421n

upstream raw materials:

1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-ol

prop-2-en-1-yl (4-methylbenzene-1-sulfonyl)carbamate

2,4-Dimethoxybenzaldehyde

Downstream raw materials:

N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-4-methylbenzenesulfonamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 916843-45-3 allyl N-[1-(2,4-dimethoxyphenyl)-3-(trifluoromethyl)but-3-en-1-yl]-N-(4-methylbenzenesulfonyl)carbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send