Technology Process of (+/-)-2-acetyl-6-(2-methoxycarbonylbenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2ol
There total 8 articles about (+/-)-2-acetyl-6-(2-methoxycarbonylbenzoyl)-5,8-dimethoxy-1,2,3,4-tetrahydro-2ol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
aluminium trichloride;
In
dichloromethane;
for 4.5h;
Ambient temperature;
DOI:10.1248/cpb.31.811
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 61 percent / 80percent formic acid / 2 h / 100 - 110 °C
2: 93 percent / sodium borohydride / ethanol / 4 h / Ambient temperature
3: tert-butyl hydroperoxide, vanadium oxyacetylacetonate / benzene / 0.75 h / Ambient temperature
4: lithium aluminium hydride / tetrahydrofuran / 4 h
5: 92 percent / triethylamine, sulfur trioxide, pyridine / dimethylsulfoxide / 1 h / Ambient temperature
6: 100 percent / anhydr. aluminium chloride / CH2Cl2 / 4.5 h / Ambient temperature
With
pyridine; tert.-butylhydroperoxide; sodium tetrahydroborate; lithium aluminium tetrahydride; aluminium trichloride; formic acid; bis(acetylacetonate)oxovanadium; sulfur trioxide; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1248/cpb.31.811
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 79 percent / tetrahydrofuran / 18 h / Ambient temperature
2: 61 percent / 80percent formic acid / 2 h / 100 - 110 °C
3: 93 percent / sodium borohydride / ethanol / 4 h / Ambient temperature
4: tert-butyl hydroperoxide, vanadium oxyacetylacetonate / benzene / 0.75 h / Ambient temperature
5: lithium aluminium hydride / tetrahydrofuran / 4 h
6: 92 percent / triethylamine, sulfur trioxide, pyridine / dimethylsulfoxide / 1 h / Ambient temperature
7: 100 percent / anhydr. aluminium chloride / CH2Cl2 / 4.5 h / Ambient temperature
With
pyridine; tert.-butylhydroperoxide; sodium tetrahydroborate; lithium aluminium tetrahydride; aluminium trichloride; formic acid; bis(acetylacetonate)oxovanadium; sulfur trioxide; triethylamine;
In
tetrahydrofuran; ethanol; dichloromethane; dimethyl sulfoxide; benzene;
DOI:10.1248/cpb.31.811
