(E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one

Base Information

• Chemical Name: (E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one
• CAS No.: 1426691-79-3
• Molecular Formula: C₂₈H₂₆O₃S₂
• Molecular Weight: 474.645
• Mol file: 1426691-79-3.mol

Synonyms:(E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one

Chemical Property of (E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one

There total 2 articles about (E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

piperonal (120-57-0,30024-74-9) + 4,4-bis(ethylthio)-1,3-diphenylbut-3-en-2-one (1256927-57-7) → (E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one (1426691-79-3)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃;

DOI:10.1039/c3cc37571d

Reference yield:

1,3-Diphenylpropanone (102-04-5) → (E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one (1426691-79-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 0 °C

1.2: 24 h / 0 - 20 °C

2.1: sodium hydroxide / ethanol / 20 °C

With potassium carbonate; sodium hydroxide; In ethanol; N,N-dimethyl-formamide;

DOI:10.1039/c3cc37571d

Reference yield: 72.0%

(E)-5-(benzo[d][1,3]dioxol-5-yl)-1,1-bis(ethylthio)-2,4-diphenylpenta-1,4-dien-3-one (1426691-79-3) → 4-(benzo[d][1,3]dioxol-5-yl)-3-(ethylthio)-2,5-diphenylcyclopent-2-enone

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; butyl-dimethylsilane; In N,N-dimethyl-formamide; at 20 - 90 ℃; for 28h; stereoselective reaction; Inert atmosphere;

DOI:10.1039/c3cc37571d

upstream raw materials:

piperonal

4,4-bis(ethylthio)-1,3-diphenylbut-3-en-2-one

1,3-Diphenylpropanone