1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan

Base Information

• Chemical Name: 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan
• CAS No.: 76196-28-6
• Molecular Formula: C₁₅H₂₄N₂O₃
• Molecular Weight: 280.367
• Mol file: 76196-28-6.mol

Synonyms:1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan

Chemical Property of 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan

There total 4 articles about 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.6%

4-<(2'-Hydroxy-3'-tert-butylamino)propoxy>acetophenone hydrochloride (76210-90-7) → 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan (76196-28-6)

Guidance literature:

With sodium hydroxide; hydroxylamine hydrochloride; In methanol; for 0.2h; Heating;

Reference yield:

4-<(2'-Hydroxy-3'-tert-butylamino)propoxy>acetophenone (42022-19-5) → 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan (76196-28-6)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; at 100 ℃; for 1h; Yield given;

DOI:10.1007/BF00765768

Reference yield:

1-[4-(2-oxiranylmethoxy)phenyl]-1-ethanone (19152-55-7) → 1-<4-(1-Oximinoethyl)phenoxy>-2-hydroxy-3-tert.-butylaminopropan (76196-28-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 2 h / 70 °C

2: aq. NH₂OH*HCl, CH₃COONa*3H₂O / ethanol / 1 h / 100 °C

With hydroxylamine hydrochloride; sodium acetate; In ethanol;

DOI:10.1007/BF00765768

upstream raw materials:

4-<(2'-Hydroxy-3'-tert-butylamino)propoxy>acetophenone

4-<(2'-Hydroxy-3'-tert-butylamino)propoxy>acetophenone hydrochloride

1-[4-(2-oxiranylmethoxy)phenyl]-1-ethanone

4-Hydroxyacetophenone