3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole

Base Information

• Chemical Name: 3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole
• CAS No.: 1580000-52-7
• Molecular Formula: C₁₄H₁₈N₂O₄S
• Molecular Weight: 310.374
• Mol file: 1580000-52-7.mol

Synonyms:3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole

Chemical Property of 3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole

There total 2 articles about 3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.8%

3-methylsulfonyl-4-methoxy-1,2,5-thiadiazole + diethylene glycol monobenzyl ether (2050-25-1,1201808-31-2) → 3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole (1580000-52-7)

Guidance literature:

diethylene glycol monobenzyl ether; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 5h; Inert atmosphere;

3-methylsulfonyl-4-methoxy-1,2,5-thiadiazole; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.bmc.2014.01.049

Reference yield: 45.51%

3-methylsulfonyl-4-methoxy-1,2,5-thiadiazole + 2,2'-[1,2-ethanediylbis(oxy)]bisethanol (112-27-6) → 3-(2-(2-(benzyloxy)ethoxy)ethoxy)-4-methoxy-1,2,5-thiadiazole (1580000-52-7) + 1,2-bis(2-(4-methoxy-1,2,5-thiadiazol-3-yloxy)ethoxy)ethane (1580000-54-9)

Guidance literature:

2,2'-[1,2-ethanediylbis(oxy)]bisethanol; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 5h; Inert atmosphere;

3-methylsulfonyl-4-methoxy-1,2,5-thiadiazole; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1016/j.bmc.2014.01.049

upstream raw materials:

diethylene glycol monobenzyl ether

2,2'-[1,2-ethanediylbis(oxy)]bisethanol