Technology Process of 11-chloro-N-cyclohexyl-5-oxo-6-propyl-5,6,7,8-tetrahydrobenzo[5,6]azepino[3,4-b]indole-7-carboxamide
There total 4 articles about 11-chloro-N-cyclohexyl-5-oxo-6-propyl-5,6,7,8-tetrahydrobenzo[5,6]azepino[3,4-b]indole-7-carboxamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; acetonitrile;
at 110 ℃;
for 2h;
regioselective reaction;
Inert atmosphere;
Sealed tube;
Microwave irradiation;
DOI:10.1021/co4001309
- Guidance literature:
-
Multi-step reaction with 2 steps
1: methanol / 72 h / 20 °C
2: potassium carbonate; palladium diacetate; triphenylphosphine / 1,4-dioxane; acetonitrile / 2 h / 110 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
palladium diacetate; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; methanol; acetonitrile;
1: |Ugi Condensation;
DOI:10.1021/co4001309
- Guidance literature:
-
Multi-step reaction with 2 steps
1: methanol / 72 h / 20 °C
2: potassium carbonate; palladium diacetate; triphenylphosphine / 1,4-dioxane; acetonitrile / 2 h / 110 °C / Inert atmosphere; Sealed tube; Microwave irradiation
With
palladium diacetate; potassium carbonate; triphenylphosphine;
In
1,4-dioxane; methanol; acetonitrile;
1: |Ugi Condensation;
DOI:10.1021/co4001309
