rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate

Base Information

Chemical Name:rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate
CAS No.:1075221-33-8
Molecular Formula:C₁₆H₁₈F₂N₂O₃
Molecular Weight:324.327
Hs Code.:

Synonyms:rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate

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Chemical Property of rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate

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Technology Process of rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate

There total 1 articles about rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 38.0%

: 1075221-30-5
benzyl 4-[3,3-difluoro-1-(4-methoxybenzyl)-4-oxoazetidin-2-yl]piperidine-1-carboxylate

: 1075221-33-8
rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate

Guidance literature:: With ammonium cerium (IV) nitrate; In water; acetonitrile; at 0 - 20 ℃; for 6.33h;
DOI:10.1002/ejoc.200800363

Reference yield: 30.0%

: 1075221-33-8
rac-benzyl 4-[3,3-difluoro-4-oxoazetidin-2-yl]piperidine-1-carboxylate

: 5437-45-6
Benzyl bromoacetate

: 1075221-50-9
benzyl rac-4-{1-[(benzyloxycarbonyl)methyl]-3,3-difluoro-4-oxoazetidin-2-yl}piperidine-1-carboxylate

Guidance literature:: With tetra-(n-butyl)ammonium iodide; N,N,N',N'-tetramethylguanidine; In acetonitrile; at 20 ℃;
DOI:10.1002/ejoc.200800363